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Introduction | Alpha-synuclein (SNCA) is abundant in the brain while smaller amounts are found in the heart, muscle, and other tissues. In the brain, alpha-synuclein is found mainly at the tips of nerve cells in presynaptic terminals. Within these structures, alpha-synuclein interacts with phospholipids and proteins. Presynaptic terminals release chemical messengers, called neurotransmitters, from compartments known as synaptic vesicles. The release of neurotransmitters relays signals between neurons and is critical for normal brain function. |
Target | Alpha Synuclein Phospho-Ser129 (SNCA pS129) |
Reactivity | Human, Mouse, Rat |
Tested Applications | ELISA |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Validity | 6 months. |
UniProt Primary AC | P37840 (UniProt, ExPASy) |
UniProt Secondary AC | A8K2A4, Q13701, Q4JHI3, Q6IAU6 |
Gene Symbol | SNCA |
GeneID | 6622 |
OMIM | 127750 |
HGNC | 11138 |
Ensembl | ENSG00000145335 |
Detection Method | Fluorometric |
Plate Coating | Uncoated |
Substrate | TMB |
Detection Antibody Conjugation | HRP |
Availability | Shipped within 1-2 weeks. |
Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |