TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C (TAF1C) Antibody

TAF1C Antibody is a Rabbit Polyclonal antibody against TAF1C. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Target	TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C (TAF1C)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 70-320 of human TAF1C.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15572 (UniProt, ExPASy)
UniProt Secondary AC	B7Z5K5, B7Z5S4, B7Z908, B7Z9L7, Q59F67, Q8N6V3
UniProt Entry Name	TAF1C_HUMAN
Gene Symbol	TAF1C
GeneID	9013
NCBI Accession	NP_001230085.1
KEGG	hsa:9013
String	9606.ENSP00000455265
Molecular Weight	Calculated MW: 95 kDa Observed MW: 110 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C (TAF1C)

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