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TATA-Box Binding Protein Associated Factor 5 (TAF5) Antibody
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Catalogue No: abx005451
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US$348.00
(Size: 60 µl)
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Datasheet SDS
TAF5 Antibody is a Rabbit Polyclonal antibody against TAF5. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex.
Research Articles on TATA-Box Binding Protein Associated Factor 5 (TAF5)
| Target | TATA-Box Binding Protein Associated Factor 5 (TAF5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TAF5 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15542 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K5B4, B2RMR0, B7ZKJ6, Q53EM4, Q5SYD5, Q86UZ7, Q9Y4K5 |
| UniProt Entry Name | TAF5_HUMAN |
| Gene Symbol | TAF5 |
| GeneID | 6877 |
| NCBI Accession | NP_008882.2 |
| KEGG | hsa:6877 |
| String | 9606.ENSP00000358854 |
| Molecular Weight | Calculated MW: 80 kDa/86 kDa Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
