Transcription Initiation Factor TFIID Subunit 6 (TAF6) Antibody

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants.

Target	Transcription Initiation Factor TFIID Subunit 6 (TAF6)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human TAF6.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49848 (UniProt, ExPASy)
UniProt Secondary AC	A4D2B2, A4D2B3, B4DT11, D6W5U2, Q6AI29
UniProt Entry Name	TAF6_HUMAN
KEGG	hsa:6878
String	9606.ENSP00000399982
Molecular Weight	Calculated MW: 72.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat TAF6.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transcription Initiation Factor TFIID Subunit 6 (TAF6)

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