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Antigen Peptide Transporter 2 (TAP2) Antibody

Catalogue No: abx001354
Price: £120.00
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Antigen Peptide Transporter 2 (TAP2) Antibody Antigen Peptide Transporter 2 (TAP2) Antibody

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TAP2 Antibody is a Rabbit Polyclonal antibody against TAP2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008].

Target TAP2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TAP2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q03519 (UniProt, ExPASy)
UniProt Secondary AC B0V2J8, O95410, Q53FI6, Q5HY71, Q96PT8, Q9UQ83
UniProt Entry Name TAP2_HUMAN
Gene Symbol TAP2
GeneID 6891
KEGG hsa:6891
String 9606.ENSP00000364034
Molecular Weight Calculated MW: 72 kDa, 75 kDa
Observed MW: 76 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Antigen Peptide Transporter 2 (TAP2) Antibody

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