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Tapasin (TAPBP) Antibody

Catalogue No: abx001603
Price: £120.00
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Tapasin (TAPBP) Antibody Tapasin (TAPBP) Antibody Tapasin (TAPBP) Antibody Tapasin (TAPBP) Antibody Tapasin (TAPBP) Antibody Tapasin (TAPBP) Antibody

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TAPBP Antibody is a Rabbit Polyclonal antibody against TAPBP. This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Target TAPBP
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TAPBP.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O15533 (UniProt, ExPASy)
UniProt Entry Name TPSN_HUMAN
Gene Symbol TAPBP
GeneID 6892
KEGG hsa:6892
String 9606.ENSP00000404833
Molecular Weight Calculated MW: 38 kDa, 43 kDa, 47 kDa, 53 kDa
Observed MW: 48 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tapasin (TAPBP) Antibody

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