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TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody

Catalogue No: abx001097
Price: £120.00
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TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody

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TARDBP Antibody is a Rabbit Polyclonal antibody against TARDBP. HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Target TAR DNA-Binding Protein 43 / TDP43 (TARDBP)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP, RIP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/20 - 1/100, IP: 1/50 - 1/100, RIP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TARDBP.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13148 (UniProt, ExPASy)
UniProt Entry Name TADBP_HUMAN
Gene Symbol TARDBP
GeneID 23435
KEGG hsa:23435
String 9606.ENSP00000240185
Molecular Weight Calculated MW: 31 kDa, 44 kDa
Observed MW: 42 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TAR DNA-Binding Protein 43 / TDP43 (TARDBP) Antibody

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