Microtubule-Associated Protein Tau (MAPT) Antibody
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Catalogue No: abx027919
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US$326.25
(Size: 80 µl)
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Datasheet SDS
MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Research Articles on Microtubule-Associated Protein Tau (MAPT)
| Target | Microtubule-Associated Protein Tau (MAPT) |
| Research Area | Metabolism, Neuroscience, Developmental Science |
| Clonality | Polyclonal |
| Reactivity | Human, Monkey |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 699-728 amino acids from human TAU (MAPT). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10636 (UniProt, ExPASy) |
| UniProt Secondary AC | P18518, Q14799, Q15549, Q15550, Q15551, Q1RMF6, Q53YB1, Q5CZI7, Q5XWF0, Q6QT54, Q9UDJ3, Q9UMH0, Q9UQ96 |
| UniProt Entry Name | TAU_HUMAN |
| Gene Symbol | MAPT |
| GeneID | 4137 |
| OMIM | 157140 |
| NCBI Accession | NP_001116538.2 NP_001116539.1 NP_001190181.1 NP_005901.2 NP_058518.1 NP_058519.3 NP_058525.1 |
| HGNC | 6893 |
| KEGG | hsa:4137 |
| Ensembl | ENSG00000186868 |
| String | 9606.ENSP00000340820 |
| Molecular Weight | Calculated MW: 78.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Reacts with Human and Cynomolgus Monkey MAPT.Predicted to react with Mouse, Rat and Cow MAPT. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |