Tubulin Beta-1 Chain (TBB1) Antibody

This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.

Target	Tubulin Beta-1 Chain (TBB1)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant human TBB1 protein.
Isotype	IgG1
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H4B7 (UniProt, ExPASy)
UniProt Entry Name	TBB1_HUMAN
String	9606.ENSP00000217133
Molecular Weight	Calculated MW: 50.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tubulin Beta-1 Chain (TBB1)

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