Serine/threonine-Protein Kinase TBK1 (TBK1) Antibody

TBK1 Antibody is a Rabbit Polyclonal antibody against TBK1. The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Target	Serine/threonine-Protein Kinase TBK1 (TBK1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TBK1/NAK.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UHD2 (UniProt, ExPASy)
UniProt Secondary AC	A8K4S4, Q8IYV3, Q9NUJ5
UniProt Entry Name	TBK1_HUMAN
Gene Symbol	TBK1
GeneID	29110
NCBI Accession	NP_037386.1
String	9606.ENSP00000329967
Molecular Weight	Calculated MW: 84 kDa Observed MW: 84 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine/threonine-Protein Kinase TBK1 (TBK1)

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