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TATA Box Binding Protein (TBP) Antibody
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Catalogue No: abx001804
Price:
£120.00
(Size: 20 µl)
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TBP Antibody is a Rabbit Polyclonal antibody against TBP. The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This protein is not suitable for samples where the nuclear envelope has been removed.
Research Articles on TATA Box Binding Protein (TBP)
| Target | TATA Box Binding Protein (TBP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human TBP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20226 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E3B3, F5H869, Q16845, Q6IBM6, Q9UC02 |
| UniProt Entry Name | TBP_HUMAN |
| Gene Symbol | TBP |
| GeneID | 6908 |
| KEGG | hsa:6908 |
| String | 9606.ENSP00000375942 |
| Molecular Weight | Calculated MW: 35 kDa, 37 kDa Observed MW: 43 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
