TATA Box Binding Protein (TBP) Antibody

Catalogue No: abx001804
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
TBP Antibody is a Rabbit Polyclonal antibody against TBP. The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This protein is not suitable for samples where the nuclear envelope has been removed.

Target TATA Box Binding Protein (TBP)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TBP.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20226 (UniProt, ExPASy)
UniProt Secondary AC B4E3B3, F5H869, Q16845, Q6IBM6, Q9UC02
UniProt Entry Name TBP_HUMAN
Gene Symbol TBP
GeneID 6908
KEGG hsa:6908
String 9606.ENSP00000375942
Molecular Weight Calculated MW: 35 kDa, 37 kDa
Observed MW: 43 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TATA Box Binding Protein (TBP)

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