Transcription Factor 4 (TCF4) Antibody

TCF4 Antibody is a Rabbit Polyclonal antibody against TCF4. This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described.

Target	Transcription Factor 4 (TCF4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TCF4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P15884 (UniProt, ExPASy)
UniProt Entry Name	ITF2_HUMAN
Gene Symbol	TCF4
GeneID	6925
NCBI Accession	NP_003190.1
KEGG	hsa:6925
String	9606.ENSP00000381382
Molecular Weight	Calculated MW: 71 kDa Observed MW: 71 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	1.10 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transcription Factor 4 (TCF4)

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