Tryptophan 2,3-Dioxygenase (TDO2) Antibody
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Catalogue No: abx005190
Price:
US$348.00
(Size: 60 µl)
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Datasheet SDS
Tryptophan 2,3-Dioxygenase (TDO2) Antibody is a Rabbit Polyclonal antibody against Tryptophan 2,3-Dioxygenase (TDO2). The TDO2 gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses. Single nucleotide polymorphisms in this gene may be associated with autism.
Research Articles on Tryptophan 2,3-Dioxygenase (TDO2)
| Target | Tryptophan 2,3-Dioxygenase (TDO2) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to Human Tryptophan 2,3-Dioxygenase (TDO2) |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P48775 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K053 |
| UniProt Entry Name | T23O_HUMAN |
| Gene Symbol | TDO2 |
| GeneID | 6999 |
| NCBI Accession | NP_005642.1 |
| KEGG | hsa:6999 |
| String | 9606.ENSP00000444788 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 48 kDa |
| Buffer | PBS, pH 7.4, containing 0.05% stabilizer, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
