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Telomeric Repeat Binding Factor 1 (TERF1) Antibody

Catalogue No: abx000566
Price: £95.00
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Telomeric Repeat Binding Factor 1 (TERF1) Antibody

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TERF1 Antibody is a Rabbit Polyclonal antibody against TERF1. Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.

Target TERF1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TERF1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UNSPSC Code 12352203
UniProt Primary AC P54274
Gene Symbol TERF1
GeneID 7013
Molecular Weight Calculated MW: 48 kDa, 50 kDa
Observed MW: 62 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Telomeric Repeat Binding Factor 1 (TERF1) Antibody

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