Telomeric Repeat-Binding Factor 1 (TERF1) Antibody
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Catalogue No: abx000566
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US$217.50
(Size: 20 µl)
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Datasheet SDS
TERF1 Antibody is a Rabbit Polyclonal antibody against TERF1. Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.
Research Articles on Telomeric Repeat-Binding Factor 1 (TERF1)
| Target | Telomeric Repeat-Binding Factor 1 (TERF1) |
| Research Area | Developmental Science |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to TERF1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P54274 (UniProt, ExPASy) |
| UniProt Secondary AC | A7XP29, Q15553, Q8NHT6, Q93029 |
| UniProt Entry Name | TERF1_HUMAN |
| Gene Symbol | TERF1 |
| GeneID | 7013 |
| OMIM | 600951 |
| NCBI Accession | NP_059523.2 |
| HGNC | 11728 |
| KEGG | hsa:7013 |
| Ensembl | ENSG00000147601 |
| String | 9606.ENSP00000276603 |
| Molecular Weight | Calculated MW: 50 kDa Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |