Transcription Factor A, Mitochondrial (TFAM) Antibody

TFAM Antibody is a Rabbit Polyclonal antibody against TFAM. This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.

Target	Transcription Factor A, Mitochondrial (TFAM)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TFAM.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q00059 (UniProt, ExPASy)
UniProt Secondary AC	A8MRB2, A9QXC6, B5BU05, Q5U0C6
UniProt Entry Name	TFAM_HUMAN
Gene Symbol	TFAM
GeneID	7019
NCBI Accession	NP_003192.1
KEGG	hsa:7019
String	9606.ENSP00000420588
Molecular Weight	Calculated MW: 29 kDa Observed MW: 22 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transcription Factor A, Mitochondrial (TFAM)

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