Trefoil Factor 3 (TFF3) Antibody

TFF3 Antibody is a Rabbit Polyclonal antibody against TFF3. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Target	Trefoil Factor 3 (TFF3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human TFF3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q07654 (UniProt, ExPASy)
UniProt Secondary AC	A0A0A6YYJ4, E9PBB5, Q96NX0, Q9UDA5
UniProt Entry Name	TFF3_HUMAN
Gene Symbol	TFF3
GeneID	7033
OMIM	600633
NCBI Accession	NP_003217.3
HGNC	11757
KEGG	hsa:7033
Ensembl	ENSG00000160180
String	9606.ENSP00000430690
Molecular Weight	Calculated MW: 9 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Trefoil Factor 3 (TFF3)

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