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Tissue Factor Pathway Inhibitor (TFPI) Antibody

Catalogue No: abx001368
Price: £120.00
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Tissue Factor Pathway Inhibitor (TFPI) Antibody Tissue Factor Pathway Inhibitor (TFPI) Antibody

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TFPI Antibody is a Rabbit Polyclonal antibody against TFPI. This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008].

Target TFPI
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TFPI.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P10646 (UniProt, ExPASy)
UniProt Secondary AC O95103, Q53TS4
UniProt Entry Name TFPI1_HUMAN
Gene Symbol TFPI
GeneID 7035
KEGG hsa:7035
String 9606.ENSP00000233156
Molecular Weight Calculated MW: 28 kDa, 35 kDa
Observed MW: 31 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tissue Factor Pathway Inhibitor (TFPI) Antibody

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