Tissue Factor Pathway Inhibitor (TFPI) Antibody
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Catalogue No: abx001368
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US$348.00
(Size: 60 µl)
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Datasheet SDS
TFPI Antibody is a Rabbit Polyclonal antibody against TFPI. This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008].
Research Articles on Tissue Factor Pathway Inhibitor (TFPI)
| Target | Tissue Factor Pathway Inhibitor (TFPI) |
| Research Area | Metabolism, Hematology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TFPI |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10646 (UniProt, ExPASy) |
| UniProt Secondary AC | O95103, Q53TS4 |
| UniProt Entry Name | TFPI1_HUMAN |
| Gene Symbol | TFPI |
| GeneID | 7035 |
| NCBI Accession | NP_001027452.1 |
| KEGG | hsa:7035 |
| String | 9606.ENSP00000233156 |
| Molecular Weight | Calculated MW: 28 kDa/35 kDa Observed MW: 32 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
