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Transforming Growth Factor Beta 2 (TGFB2) Antibody
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Catalogue No: abx025258
Price:
US$623.50
(Size: 100 µl)
Orders to United States ship from United States
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This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t (1;7) (q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. This antibody is supplied as crude ascites.
Research Articles on Transforming Growth Factor Beta 2 (TGFB2)
| Target | Transforming Growth Factor Beta 2 (TGFB2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human TGFB2 recombinant protein. |
| Isotype | IgG1 Kappa |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P61812 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DKC5, P08112, Q15579, Q15581, Q4VAV9 |
| UniProt Entry Name | TGFB2_HUMAN |
| KEGG | hsa:7042 |
| String | 9606.ENSP00000355896 |
| Molecular Weight | Calculated MW: 47.7 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Please enquire. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |