Transforming Growth Factor Beta Induced Protein (TGFBI) Antibody

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

Target	Transforming Growth Factor Beta Induced Protein (TGFBI)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human TGFBI.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15582 (UniProt, ExPASy)
UniProt Entry Name	BGH3_HUMAN
KEGG	hsa:7045
String	9606.ENSP00000416330
Molecular Weight	Calculated MW: 74.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Cow, Pig and Rabbit TGFBI.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transforming Growth Factor Beta Induced Protein (TGFBI)

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