TGFB Induced Factor Homeobox 1 (TGIF1) Antibody

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Catalogue No: abx028149
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described.

Target TGFB Induced Factor Homeobox 1 (TGIF1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human TGIF1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15583 (UniProt, ExPASy)
UniProt Secondary AC A6NE42, A6NLU7, F8VZB6, Q6ICR0, Q8N5X9, Q9NRS0
UniProt Entry Name TGIF1_HUMAN
KEGG hsa:7050
String 9606.ENSP00000327959
Molecular Weight Calculated MW: 43 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TGFB Induced Factor Homeobox 1 (TGIF1)


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