Thrombomodulin (THBD) Antibody
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Catalogue No: abx003069
Price:
US$348.00
(Size: 60 µl)
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Datasheet SDS
THBD Antibody is a Rabbit Polyclonal antibody against THBD. The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Research Articles on Thrombomodulin (THBD)
| Target | Thrombomodulin (THBD) |
| Research Area | Metabolism, Hematology, Cardiovascular Biology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CD141/Thrombomodulin |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P07204 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8IV29, Q9UC32 |
| UniProt Entry Name | TRBM_HUMAN |
| Gene Symbol | THBD |
| GeneID | 7056 |
| NCBI Accession | NP_000352.1 |
| KEGG | hsa:7056 |
| String | 9606.ENSP00000366307 |
| Molecular Weight | Calculated MW: 60 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
