Thyroid Hormone Receptor Beta (THRB) Antibody

Catalogue No: abx001332
Price: £120.00
(Size: 20 µl)
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THRB Antibody is a Rabbit Polyclonal antibody against THRB. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].

Target Thyroid Hormone Receptor Beta (THRB)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to 1-263 AA of human THRB.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P10828 (UniProt, ExPASy)
UniProt Secondary AC B3KU79, P37243, Q13986, Q3KP35, Q6WGL2, Q9UD41
UniProt Entry Name THB_HUMAN
Gene Symbol THRB
GeneID 7068
KEGG hsa:7068
String 9606.ENSP00000379904
Molecular Weight Calculated MW: 52 kDa, 54 kDa
Observed MW: 53 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 0.91 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Thyroid Hormone Receptor Beta (THRB)

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