Protein Timeless Homolog (TIMELESS) Antibody

TIMELESS Antibody is a Rabbit Polyclonal antibody against TIMELESS. The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.

Target	Protein Timeless Homolog (TIMELESS)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 969-1208 of human TIMELESS.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UNS1 (UniProt, ExPASy)
UniProt Secondary AC	B2ZAV0, O94802, Q86VM1, Q8IWH3
UniProt Entry Name	TIM_HUMAN
Gene Symbol	TIMELESS
GeneID	8914
NCBI Accession	NP_003911.2
String	9606.ENSP00000450607
Molecular Weight	Calculated MW: 139 kDa Observed MW: 160 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Timeless Homolog (TIMELESS)

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