Metalloproteinase Inhibitor 2 (TIMP2) Antibody
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Catalogue No: abx001309
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US$348.00
(Size: 60 µl)
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Datasheet SDS
TIMP2 Antibody is a Rabbit Polyclonal antibody against TIMP2. This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Research Articles on Metalloproteinase Inhibitor 2 (TIMP2)
| Target | Metalloproteinase Inhibitor 2 (TIMP2) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human TIMP2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P16035 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16121, Q93006, Q9UDF7 |
| UniProt Entry Name | TIMP2_HUMAN |
| Gene Symbol | TIMP2 |
| GeneID | 7077 |
| NCBI Accession | NP_003237.2 |
| KEGG | hsa:7077 |
| String | 9606.ENSP00000262768 |
| Molecular Weight | Calculated MW: 24 kDa Observed MW: 26 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
