Metalloproteinase Inhibitor 2 (TIMP2) Antibody

Catalogue No: abx001309
Price: £120.00
(Size: 20 µl)
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TIMP2 Antibody is a Rabbit Polyclonal antibody against TIMP2. This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Target Metalloproteinase Inhibitor 2 (TIMP2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TIMP2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16035 (UniProt, ExPASy)
UniProt Secondary AC Q16121, Q93006, Q9UDF7
UniProt Entry Name TIMP2_HUMAN
Gene Symbol TIMP2
GeneID 7077
KEGG hsa:7077
String 9606.ENSP00000262768
Molecular Weight Calculated MW: 24 kDa
Observed MW: 22 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.36 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Metalloproteinase Inhibitor 2 (TIMP2)

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