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Toll-Like Receptor 1 (TLR1) Antibody

Catalogue No: abx000950
Price: £120.00
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Toll-Like Receptor 1 (TLR1) Antibody

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TLR1 Antibody is a Rabbit Polyclonal antibody against TLR1. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Target Toll Like Receptor 1 (TLR1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TLR1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15399 (UniProt, ExPASy)
UniProt Secondary AC D1CS39, D1CS41, O15452, Q32MK3, Q32MK4, Q9UG90
UniProt Entry Name TLR1_HUMAN
Gene Symbol TLR1
GeneID 7096
OMIM 601194
HGNC 11847
KEGG hsa:7096
Ensembl ENSG00000174125
String 9606.ENSP00000354932
Molecular Weight Calculated MW: 90 kDa
Observed MW: 100 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Toll-Like Receptor 1 (TLR1) Antibody

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