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Toll Like Receptor 2 (TLR2) Antibody
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Catalogue No: abx027542
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Research Articles on Toll Like Receptor 2 (TLR2)
| Target | Toll Like Receptor 2 (TLR2) |
| Research Area | Tumor Immunity, Infection Immunity, Immunology, Pulmonology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 281-310 amino acids from the Central region of human TLR2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O60603 (UniProt, ExPASy) |
| UniProt Secondary AC | B3Y612, D1CS45, D1CS48, D1CS49, O15454, Q8NI00 |
| Gene Symbol | TLR2 |
| GeneID | 7097 |
| OMIM | 246300 |
| NCBI Accession | NP_003255.2 |
| HGNC | 11848 |
| KEGG | hsa:7097 |
| Ensembl | ENSG00000137462 |
| String | 9606.ENSP00000260010 |
| Molecular Weight | Calculated MW: 89.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |