Toll Like Receptor 2 (TLR2) Antibody

Catalogue No: abx001983
Price: £120.00
(Size: 20 µl)
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TLR2 Antibody is a Rabbit Polyclonal antibody against TLR2. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Target Toll Like Receptor 2 (TLR2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TLR2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O60603 (UniProt, ExPASy)
UniProt Secondary AC B3Y612, D1CS45, D1CS48, D1CS49, O15454, Q8NI00
Gene Symbol TLR2
GeneID 7097
OMIM 246300
NCBI Accession NP_003255.2
HGNC 11848
KEGG hsa:7097
Ensembl ENSG00000137462
String 9606.ENSP00000260010
Molecular Weight Calculated MW: 89 kDa
Observed MW: 100 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Toll Like Receptor 2 (TLR2)

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