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Toll Like Receptor 2 (TLR2) Antibody
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Catalogue No: abx001983
Price:
£120.00
(Size: 20 µl)
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TLR2 Antibody is a Rabbit Polyclonal antibody against TLR2. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
Research Articles on Toll Like Receptor 2 (TLR2)
| Target | Toll Like Receptor 2 (TLR2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human TLR2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O60603 (UniProt, ExPASy) |
| UniProt Secondary AC | B3Y612, D1CS45, D1CS48, D1CS49, O15454, Q8NI00 |
| Gene Symbol | TLR2 |
| GeneID | 7097 |
| OMIM | 246300 |
| NCBI Accession | NP_003255.2 |
| HGNC | 11848 |
| KEGG | hsa:7097 |
| Ensembl | ENSG00000137462 |
| String | 9606.ENSP00000260010 |
| Molecular Weight | Calculated MW: 89 kDa Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
