Transmembrane Channel-Like Protein 6 (TMC6) Antibody
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Catalogue No: abx027882
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.
Research Articles on Transmembrane Channel-Like Protein 6 (TMC6)
| Target | Transmembrane Channel-Like Protein 6 (TMC6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 160-188 amino acids from the N-terminal region of human TMC6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q7Z403 (UniProt, ExPASy) |
| UniProt Secondary AC | O43284, Q45VJ2, Q8IU98, Q8IUI7, Q8IWU8, Q8TEQ7, Q9HAG5 |
| UniProt Entry Name | TMC6_HUMAN |
| Gene Symbol | TMC6 |
| KEGG | hsa:11322 |
| String | 9606.ENSP00000465261 |
| Molecular Weight | Calculated MW: 90 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |