Transmembrane Protein 27 (TMEM27) Antibody

TMEM27 Antibody is a Rabbit Polyclonal antibody against TMEM27. This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells.

Target	Transmembrane Protein 27 (TMEM27)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human TMEM27.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9HBJ8 (UniProt, ExPASy)
UniProt Secondary AC	B2R9M1, Q6UW07
UniProt Entry Name	CLTRN_HUMAN
Gene Symbol	CLTRN
GeneID	57393
NCBI Accession	NP_065716.1
String	9606.ENSP00000369699
Molecular Weight	Calculated MW: 25 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transmembrane Protein 27 (TMEM27)

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