Tumor Necrosis Factor (TNF) Antibody
REQUEST MORE INFO
Catalogue No: abx126717
Price:
US$217.50
(Size: 20 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
Tumor Necrosis Factor (TNF) Antibody is a Rabbit polyclonal against Tumor Necrosis Factor (TNF). Tumor Necrosis Factor (TNF) is a multifunctional proinflammatory cytokine that belongs to the Tumor Necrosis Factor (TNF) superfamily. It is mainly secreted by macrophages and functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation and has been implicated in a variety of diseases, including autoimmune disease, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in the TNF gene are linked to susceptibility to cerebral malaria, septic shock, and Alzheimer's disease.
Research Articles on Tumor Necrosis Factor (TNF)
| Target | Tumor Necrosis Factor (TNF) |
| Research Area | Cytokines, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/500 - 1/1000, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to TNF. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01375 (UniProt, ExPASy) |
| UniProt Secondary AC | O43647, Q9P1Q2, Q9UIV3 |
| UniProt Entry Name | TNFA_HUMAN |
| Gene Symbol | TNF |
| GeneID | 7124 |
| OMIM | 191160 |
| NCBI Accession | NP_000585.2 |
| HGNC | 11892 |
| KEGG | hsa:7124 |
| Ensembl | ENSG00000232810 |
| String | 9606.ENSP00000398698 |
| Molecular Weight | Calculated MW: 26 kDa Observed MW: 18 kDa, 25 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | 1.84 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |