Tumor Necrosis Factor Alpha (TNFA) Antibody

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Catalogue No: abx000662
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
TNF Antibody is a Rabbit Polyclonal antibody against TNF. This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Target Tumor Necrosis Factor Alpha (TNFA)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/1000 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TNF.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01375 (UniProt, ExPASy)
UniProt Secondary AC O43647, Q9P1Q2, Q9UIV3
UniProt Entry Name TNFA_HUMAN
Gene Symbol TNF
GeneID 7124
KEGG hsa:7124
String 9606.ENSP00000398698
Molecular Weight Calculated MW: 25 kDa
Observed MW: 28 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tumor Necrosis Factor Alpha (TNFA)


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