Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3) Antibody

TNFAIP3 Antibody is a Rabbit Polyclonal antibody against TNFAIP3. This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.

Target	Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 600-738 of human TNFAIP3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P21580 (UniProt, ExPASy)
UniProt Secondary AC	B2R767, E1P588, Q2HIX9, Q5VXQ7, Q9NSR6
UniProt Entry Name	TNAP3_HUMAN
Gene Symbol	TNFAIP3
GeneID	7128
NCBI Accession	NP_006281.1
KEGG	hsa:7128
String	9606.ENSP00000481570
Molecular Weight	Calculated MW: 90 kDa Observed MW: 90 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Alpha-Induced Protein 3 (TNFAIP3)

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