Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) Antibody

Catalogue No: abx001148
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
TNFRSF10B Antibody is a Rabbit Polyclonal antibody against TNFRSF10B. The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Target Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TNFRSF10B.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14763 (UniProt, ExPASy)
UniProt Secondary AC O14720, O15508, O15517, O15531, Q6UXM8, Q7Z360, Q9BVE0
UniProt Entry Name TR10B_HUMAN
Gene Symbol TNFRSF10B
GeneID 8795
KEGG hsa:8795
String 9606.ENSP00000276431
Molecular Weight Calculated MW: 12 kDa, 45 kDa, 47 kDa
Observed MW: 48 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B)

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