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Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) Antibody
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Catalogue No: abx001712
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US$348.00
(Size: 60 µl)
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TNFRSF11B Antibody is a Rabbit Polyclonal antibody against TNFRSF11B. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TNFRSF11B |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00300 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9A8, O60236, Q53FX6, Q9UHP4 |
| UniProt Entry Name | TR11B_HUMAN |
| Gene Symbol | TNFRSF11B |
| GeneID | 4982 |
| NCBI Accession | NP_002537.3 |
| KEGG | hsa:4982 |
| String | 9606.ENSP00000297350 |
| Molecular Weight | Calculated MW: 46 kDa Observed MW: 48 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
