Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14) Antibody

TNFRSF14 Antibody is a Rabbit Polyclonal antibody against TNFRSF14. The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes.

Target	Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 39-202 of human HVEM/TNFRSF14.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92956 (UniProt, ExPASy)
UniProt Secondary AC	B3KW30, B9DI89, Q6IB95, Q8N634, Q8WXR1, Q96J31, Q9UM65
UniProt Entry Name	TNR14_HUMAN
Gene Symbol	TNFRSF14
GeneID	8764
NCBI Accession	NP_003811.2
KEGG	hsa:8764
String	9606.ENSP00000347948
Molecular Weight	Calculated MW: 30 kDa Observed MW: 30 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14)

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