Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14) Antibody
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Catalogue No: abx001604
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US$217.50
(Size: 20 µl)
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Datasheet SDS
TNFRSF14 Antibody is a Rabbit Polyclonal antibody against TNFRSF14. The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 14 (TNFRSF14) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to TNFRSF14. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q92956 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KW30, B9DI89, Q6IB95, Q8N634, Q8WXR1, Q96J31, Q9UM65 |
| UniProt Entry Name | TNR14_HUMAN |
| Gene Symbol | TNFRSF14 |
| GeneID | 8764 |
| NCBI Accession | NP_003811.2 |
| KEGG | hsa:8764 |
| String | 9606.ENSP00000347948 |
| Molecular Weight | Calculated MW: 30 kDa Observed MW: 30 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |