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Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A) Antibody

Catalogue No: abx001297
Price: £120.00
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TNFRSF1A Antibody is a Rabbit Polyclonal antibody against TNFRSF1A. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.

Target Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TNF-R1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P19438 (UniProt, ExPASy)
UniProt Entry Name TNR1A_HUMAN
Gene Symbol TNFRSF1A
GeneID 7132
String 9606.ENSP00000162749
Molecular Weight Calculated MW: 24 kDa, 25 kDa, 38 kDa, 50 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A) Antibody

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