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Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A) Antibody
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Catalogue No: abx001297
Price:
£120.00
(Size: 20 µl)
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TNFRSF1A Antibody is a Rabbit Polyclonal antibody against TNFRSF1A. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human TNF-R1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19438 (UniProt, ExPASy) |
| UniProt Entry Name | TNR1A_HUMAN |
| Gene Symbol | TNFRSF1A |
| GeneID | 7132 |
| KEGG | hsa:7132 |
| String | 9606.ENSP00000162749 |
| Molecular Weight | Calculated MW: 24 kDa, 25 kDa, 38 kDa, 50 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
