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Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B) Antibody

Catalogue No: abx001016
Price: £120.00
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TNFRSF1B Antibody is a Rabbit Polyclonal antibody against TNFRSF1B. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Target Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TNFRSF1B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20333 (UniProt, ExPASy)
UniProt Secondary AC B1AJZ3, Q16042, Q6YI29, Q9UIH1
Gene Symbol TNFRSF1B
GeneID 7133
Molecular Weight Calculated MW: 28 kDa, 48 kDa
Observed MW: 64 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B) Antibody

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