Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody

TNFRSF4 Antibody is a Rabbit Polyclonal antibody against TNFRSF4. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

Target	Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4)
Clonality	Polyclonal
Reactivity	Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD134/OX40.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P43489 (UniProt, ExPASy)
UniProt Secondary AC	Q13663, Q2M312, Q5T7M0
UniProt Entry Name	TNR4_HUMAN
Gene Symbol	TNFRSF4
GeneID	7293
NCBI Accession	NP_003318.1
KEGG	hsa:7293
String	9606.ENSP00000368538
Molecular Weight	Calculated MW: 29 kDa Observed MW: 48 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4)

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