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Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) Antibody
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Catalogue No: abx002630
Price:
US$348.00
(Size: 60 µl)
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TNFRSF4 Antibody is a Rabbit Polyclonal antibody against TNFRSF4. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 4 / CD134 (TNFRSF4) |
| Clonality | Polyclonal |
| Reactivity | Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human CD134/OX40 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P43489 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13663, Q2M312, Q5T7M0 |
| UniProt Entry Name | TNR4_HUMAN |
| Gene Symbol | TNFRSF4 |
| GeneID | 7293 |
| NCBI Accession | NP_003318.1 |
| KEGG | hsa:7293 |
| String | 9606.ENSP00000368538 |
| Molecular Weight | Calculated MW: 29 kDa Observed MW: 48 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
