Tumor Necrosis Factor Receptor Superfamily Member 8 / CD30 (TNFRSF8) Antibody
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Catalogue No: abx025475
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US$623.50
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. This antibody is supplied as crude ascites.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 8 / CD30 (TNFRSF8)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 8 / CD30 (TNFRSF8) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Apoptosis, Tumor Immunity, Reproductive Science, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/100 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 294-321 amino acids from the Central region of human TNFRSF8/CD30. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P28908 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AN79, B9EGD9, D3YTD8, Q6P4D9 |
| UniProt Entry Name | TNR8_HUMAN |
| KEGG | hsa:943 |
| String | 9606.ENSP00000263932 |
| Molecular Weight | Calculated MW: 63.7 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |