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Tyrosine Kinase, Non Receptor 2 / ACK1 (TNK2) Antibody

Catalogue No: abx001966
Price: £120.00
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Tyrosine Kinase, Non Receptor 2 / ACK1 (TNK2) Antibody Tyrosine Kinase, Non Receptor 2 / ACK1 (TNK2) Antibody

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TNK2 Antibody is a Rabbit Polyclonal antibody against TNK2. This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

Target TNK2
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TNK2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07912 (UniProt, ExPASy)
UniProt Secondary AC Q6ZMQ0, Q8N6U7, Q96H59
UniProt Entry Name ACK1_HUMAN
Gene Symbol TNK2
GeneID 10188
KEGG hsa:10188
String 9606.ENSP00000371341
Molecular Weight Calculated MW: 60 kDa, 114 kDa, 119 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tyrosine Kinase, Non Receptor 2 / ACK1 (TNK2) Antibody

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