Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1) Antibody

TNNC1 Antibody is a Rabbit Polyclonal antibody against TNNC1. Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Target	Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1)
Clonality	Polyclonal
Reactivity	Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TNNC1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P63316 (UniProt, ExPASy)
UniProt Secondary AC	O14800, P02590, P04463
UniProt Entry Name	TNNC1_HUMAN
Gene Symbol	TNNC1
GeneID	7134
NCBI Accession	NP_003271.1
KEGG	hsa:7134
String	9606.ENSP00000232975
Molecular Weight	Calculated MW: 18 kDa Observed MW: 18 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Troponin C, Slow Skeletal And Cardiac Muscles (TNNC1)

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