Cardiac Troponin T2 (TNNT2) Antibody

Cardiac Troponin T2 (TNNT2) Antibody is a Rabbit Polyclonal antibody against Cardiac Troponin T2 (TNNT2). The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Target	Cardiac Troponin T2 (TNNT2)
Clonality	Polyclonal
Reactivity	Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IHC-P: 1/100 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Cardiac troponin T (TNNT2).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P45379 (UniProt, ExPASy)
UniProt Secondary AC	A2TDB9, A8K3K6, O60214, Q99596, Q99597, Q9BUF6, Q9UM96
UniProt Entry Name	TNNT2_HUMAN
Gene Symbol	TNNT2
GeneID	7139
OMIM	115195
NCBI Accession	NP_001001432.1 NM_001001432.2
HGNC	11949
Ensembl	ENSG00000118194
String	9606.ENSP00000236918
Molecular Weight	Calculated MW: 36 kDa Observed MW: 42 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cardiac Troponin T2 (TNNT2)

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