Toll Like Receptor 4 (TLR4) Antibody

Toll Like Receptor 4 (TLR4) Antibody is a Mouse Monoclonal antibody for the detection of TLR4.

TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Target	Toll Like Receptor 4 (TLR4)
Clonality	Monoclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Mouse
Recommended dilutions	WB: 1/1000 - 1/8000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	toll-like receptor 4
Isotype	IgG2b
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	O00206 (UniProt, ExPASy)
Gene Symbol	TLR4
GeneID	7099
OMIM	603030
HGNC	11850
Ensembl	ENSG00000136869
Molecular Weight	Observed MW: 100 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Toll Like Receptor 4 (TLR4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue