Toll-Like Receptor 5 (TLR5) Antibody

Catalogue No: abx001438
Price: £120.00
(Size: 20 µl)
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Toll-Like Receptor 5 (TLR5) Antibody

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TLR5 Antibody is a Rabbit Polyclonal antibody against TLR5. This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009].

Target TLR5
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TLR5.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O60602 (UniProt, ExPASy)
UniProt Entry Name TLR5_HUMAN
Gene Symbol TLR5
GeneID 7100
KEGG hsa:7100
String 9606.ENSP00000440643
Molecular Weight Calculated MW: 97 kDa
Observed MW: 100 kDa
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Toll-Like Receptor 5 (TLR5) Antibody

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