Menu

Cellular Tumor Antigen P53 (TP53) Antibody

Catalogue No: abx002285
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Cellular Tumor Antigen P53 (TP53) Antibody Cellular Tumor Antigen P53 (TP53) Antibody Cellular Tumor Antigen P53 (TP53) Antibody Cellular Tumor Antigen P53 (TP53) Antibody Cellular Tumor Antigen P53 (TP53) Antibody

Available Options

* Size:




TP53 Antibody is a Rabbit Polyclonal antibody against TP53. This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity.

Target Cellular Tumor Antigen P53 (TP53)
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TP53.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04637 (UniProt, ExPASy)
UniProt Entry Name P53_HUMAN
Gene Symbol TP53
GeneID 7157
KEGG hsa:7157
String 9606.ENSP00000269305
Molecular Weight Calculated MW: 23-43 kDa
Observed MW: 53 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cellular Tumor Antigen P53 (TP53) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good