Tryptophan 5-Hydroxylase 1 (TPH1) Antibody

TPH1 Antibody is a Rabbit Polyclonal antibody against TPH1. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Target	Tryptophan 5-Hydroxylase 1 (TPH1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 345-444 of human TPH1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17752 (UniProt, ExPASy)
UniProt Secondary AC	D3DQX6, O95188, O95189, Q16736, Q3KPG8
Gene Symbol	TPH1
GeneID	7166
NCBI Accession	NP_004170.1
Molecular Weight	Calculated MW: 51 kDa Observed MW: 51 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tryptophan 5-Hydroxylase 1 (TPH1)

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