Tryptophan Hydroxylase 2 (TPH2) Antibody
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Catalogue No: abx005394
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US$217.50
(Size: 20 µl)
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Datasheet SDS
TPH2 Antibody is a Rabbit Polyclonal antibody against TPH2. This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.
Research Articles on Tryptophan Hydroxylase 2 (TPH2)
| Target | Tryptophan Hydroxylase 2 (TPH2) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to TPH2. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8IWU9 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NGA4, Q14CB0 |
| UniProt Entry Name | TPH2_HUMAN |
| Gene Symbol | TPH2 |
| GeneID | 121278 |
| NCBI Accession | NP_775489.2 |
| KEGG | hsa:121278 |
| String | 9606.ENSP00000329093 |
| Molecular Weight | Calculated MW: 56 kDa Observed MW: 56/52 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |