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Tropomyosin 1 (TPM1) Antibody

Catalogue No: abx001071
Price: £60.00
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Tropomyosin 1 (TPM1) Antibody

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TPM1 Antibody is a Rabbit Polyclonal antibody against TPM1. This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

Target TPM1
Clonality Polyclonal
Reactivity Human, Mouse, Zebrafish
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TPM1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P09493 (UniProt, ExPASy)
UniProt Entry Name TPM1_HUMAN
Gene Symbol TPM1
GeneID 7168
Molecular Weight Calculated MW: 26 kDa, 28 kDa, 32 kDa
Observed MW: 36 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tropomyosin 1 (TPM1) Antibody

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