Tropomyosin Beta Chain (TPM2) Antibody

TPM2 Antibody is a Rabbit Polyclonal antibody against TPM2. This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Tropomyosin Beta Chain (TPM2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100, IP: 0.5-4 µg/400-600 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TPM2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P07951 (UniProt, ExPASy)
UniProt Secondary AC	A6NM85, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67
UniProt Entry Name	TPM2_HUMAN
Gene Symbol	TPM2
GeneID	7169
NCBI Accession	NP_003280.2
KEGG	hsa:7169
Molecular Weight	Calculated MW: 33 kDa Observed MW: 36 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tropomyosin Beta Chain (TPM2)

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